ABSTRACT
Abstract This study aimed to compare the linear dimensions of the dental arches of adult patients with complete unilateral cleft lip and palate (UCLP) after orthodontic and prosthetic treatment with fixed partial dentures (FPD) to patients without clefts, using 3D technology. This retrospective longitudinal study sample consisted of 35 subjects divided into two groups. Included in this sample were 15 complete UCLP individuals who had received orthodontic treatment before rehabilitation with a fixed partial denture (FG), as well as 20 patients without cleft as control group (CG). All patients were aged between 18 and 30 years. Digital dental casts were obtained in two stages: (T1) end of orthodontic treatment and (T2) one year after prosthetic rehabilitation (FG); and (T1) end of orthodontic treatment and (T2) one year after removal of the orthodontic appliance (CG). Intercanine, interfirst premolar and intermolar distances, and incisor-molar length were obtained. A precalibrated and trained examiner performed the assessments. Intergroup differences between T2 and T1 were compared between the groups using the t test or Mann-Whitney test with a significance level of 5% (p<0.05). The intercanine distance variation (T2-T1) showed statistical difference (p=0.005) increasing in the FG group and decreasing in the CG group. In the interfirst premolar distance variation, FG decreased, while CG increased with statistically significant difference (p=0.008). The intercanine distance of individuals with cleft showed stability, while that of the CG had no stability. The CG showed stability in the interfirst premolar distance, while FG had no stability. These findings showed that the FPD is capable of restricting orthodontic results, leading to a stabilization of the dental arches.
Subject(s)
Humans , Male , Female , Adolescent , Adult , Young Adult , Orthodontics, Corrective/methods , Cleft Lip/rehabilitation , Cleft Palate/rehabilitation , Dental Prosthesis, Implant-Supported/methods , Imaging, Three-Dimensional/methods , Dental Arch/pathology , Orthodontic Appliances , Reference Values , Retrospective Studies , Cleft Lip/pathology , Cleft Palate/pathology , Treatment Outcome , Statistics, Nonparametric , Anatomic Landmarks , Maxilla/pathologyABSTRACT
Objetivo: Avaliar o efeito do antiinflamatório não-esteroidal Rofecoxib (Vioxx®) no processo de reparo ósseo em tíbias de ratos estressados. Métodos: Foram utilizados 48 ratos (Albinus Wistar), machos, com peso entre 150 e 200 gramas e divididos em três grupos com 16 animais cada. Foram realizados os seguintes procedimentos: o grupo I foi utilizado como grupo controle e nele foi realizado apenas o defeito ósseo; no grupo II os animais receberam estímulo estressor nos três dias pré-operatórios e nos dias pós-operatórios, após a realização do defeito, até o sacrifício; no grupo III os animais receberam a administração do antiinflamatório não-esteroidal (préoperatório), estímulo estressor uma hora após a administração da droga, no período pré-operatório, defeito ósseo e estresse no período pós-operatório, até o respectivo sacrifício. Em grupos de quatro, os animais foram sacrificados aos 7, 14, 30 e 60 dias pós-operatórios, por meio de deslocamento da coluna cervical. Em seguida ao sacrifício, as tíbias direita e esquerda foram removidas, fixadas em formalina, descalcificadas em ácido etilenodiaminatetracético (Na.2H2.2H2O) e incluídas em parafina. Os cortes com seis micrometros de espessura foram corados pela hematoxilina e eosina para análise microscópica. Resultados: Os resultados obtidos foram descritos em função do tempo pós-operatório das ocorrências histomorfológicas observadas em diferentes grupos experimentais. Conclusão: Os resultados obtidos permitiram concluir que: 1) a reparação do defeito ósseo provocado nos ratos do grupo II mostrou-se mais atrasada que a do grupo I; 2) a reparação do defeito ósseo provocada nos ratos do grupo III mostrou-se menos atrasada que a do grupo II; 3) a prescrição do antiinflamatório Rofecoxib pode ser indicada no caso de experimentos de animais estressados porque diminui o efeito do estresse sobre o reparo ósseo, no caso de defeitos provocados na tíbia de ratos.
Objective: To evaluate the effect of the nonsteroidal anti-inflammatory drug Rofecoxib (Vioxx) on the bone repair process in the tibiae of stressed rats. Methods: In this study, use was made of 48 young male (Albinus Wistar) rats weighing between 150 and 200 grams, divided into three groups of 16 animals each. The following procedures were performed: Group I was used as the control group, and in it, only the bone defect was performed; in Group II the animals received stressor stimulus in the three pre-operative days and three post- operative days after the defect was performed, up to the time of sacrifice; in Group III the animals received the administration of nonsteroidal anti-inflammatory medication (pre-operatively), stressor stimulus one hour after drug administration, in the pre-operative period, bone defect and stress in the post-operative period, up to the time of sacrifice. In groups of four, the animals were sacrificed at 7, 14, 30 and 60 post-operative days, by means of cervical column dislocation. After being sacrificed, the right and left tibiae were removed, fixed in formalin, decalcified in ethylenodiaminatetracetic acid (Na.2H2.2H2O) and included in paraffin. Cuts of 6 micrometers thickness were stained with hematoxylin and eosin for microscopic analysis. Results: The results obtained were described as a function of the post-operative time of the histomorphologic occurrences observed in the different experimental groups. Conclusion: The results allowed one to conclude that: 1) repair of the bone defect caused in the rats of Group II were shown to be more delayed than those in Group I; 2) repair of the bone defect caused in the rats of Group III were shown to be less delayed than those in Group II; 3) the prescription of the anti-inflammatory drug Rofecoxib can be indicated in the case of experiments with stressed animals, because it diminished the effect of stress on bone repair, in the case of defects caused in the tibia of rats.
Subject(s)
Animals , Rats , Anti-Inflammatory Agents, Non-Steroidal , Bone Regeneration , TibiaABSTRACT
Os autores, através da descriçäo de caso de rânula, abordam sua definiçäo, etiopatogenia, características histológicas, diagnóstico diferencial e modalidades de tratamento, indicando a excisäo da lesäo sem utilizaçäo de marsupializaçäo prévia
Subject(s)
Humans , Male , Child , Mucocele , RanulaABSTRACT
Apesar de já ter sido provado o alto risco de contágio durante procedimentos cirúrgicos odontológicos, por doenças tais como a hepatite B, herpes, HIV, tuberculose e outras, os dentistas ainda näo têm se mostrado eficientes no controle de infecçöes, seja antes, durante ou após a execuçäo da cirurgia. Este trabalho tem como objetivo descrever técnicas e materiais disponíveis para este controle